In mice,the dominant allele Gs of the X-linked gene Greasy produces shiny fur,wh

Question

In mice,the dominant allele Gs of the X-linked gene Greasy produces shiny fur,while the recessive wild type Gs+ produces normal fur. The dominant allele Bhd of the X-linked Broadhead gene causes skeletal abnormalities including broad heads and snouts,while the recessive wild type Bhd+allele produces normal skeletons. Female mice heterozygous for both genes were mated to wild type males.Of the 100 male offspring scored in this,49 had shiny fur,48 had skeletal abnormalities,2 had shiny fur and skeletal abnormalities,and 1 was wild type.What is the genotype of the heterozygous female? a). Gs/Gs+;Bhd/Bhd+ b). GsBhd/Gs+Bhd c).Gs Bhd+/Gs+Bhd d). there's not enough data to tell.

Questions 5
Based the data from Questions 4 above what is the RF value for these two genes? a). 0.5 b).0.03 c).0.015 d).0.02 for Gs and 0.01 for Bhd e). you can't tell because only males were scored.

Explanation / Answer

What is the genotype of the heterozygous female?

c) Gs Bhd+/Gs+Bh

The cross can be diagrammed:

Gs Bhd+/Gs+ Bhd X Gs+ Bhd+/Y 49 Gs Bhd+ : 48 Gs+ Bhd : 2 Gs Bhd : 1 Gs+ Bhd+

What is the RF value for these two genes?

b).0.03

RF= (2+1)/100=0.03=3mu

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