Is Rubella virus associated with higher levels of birth defect? Mothers who cont
ID: 190637 • Letter: I
Question
Is Rubella virus associated with higher levels of birth defect?
Mothers who contract rubella during lattrer part of pregnancies have babies with higher rates of cardiac, visio and hearing disoders.
To test their observation, Dr Kulkarni studies more than 1200 pregnant women in 4 hospitals over a period of 7 years. Of the 1200, they tracked the mothers health during the final trimester,a nd infant health during the first year after birth. When a mother shows visible sympotoms of rubella, Dr Kulkarnis team noted the severity and duration of her symptoms. From their data, the observed that women who showed symptoms of rubella were 200 times more likely than women with no symptoms to give birth to a baby with heart problems, blindness and deafness.
A. What was the independent variable?
B. What was the dependent variable?
C. What was the control?
D. What was the constant
E. What type of study is this? Explain
Explanation / Answer
A. The subjects (pregnant women) were the independent variable. They were selected independently from 4 different hospitals.
B. Infants' birth defect was the dependent variable. It was dependent on the health (rubella symptoms) of their mothers while pregnant.
C. Pregnant women without any symptoms were the control.
D. The sample size (n=1200) , that is, the number of pregnant women under observation was constant.
E. This is a cross sectional study, which analyzes data from a population, or a representative subset at a specific point in time.
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