part a and b please 3. Consider the replication of poly-dA/poly-dT, which produc

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part a and b please

3. Consider the replication of poly-dA/poly-dT, which produces the following region near the start of an Okazaki fragment: The. denote the continuation of the nucleic acid a. Which stretch of nucleotides is the primer of the Okazaki fragment? b. Label the point of the "nick the place in this localized region where the phosphodiester back bone of the nucleic acid is not linked together. c. In a series of sketches, show the result of action by DNA polymerase I (consider the DNA above to be in a bacterium). You should show the DNA polymerase I after binding to the nick and before starting the exonuclease/polymerase reactions. You should then show DNA polymerase I after it has moved about halfway through the primer. The last sketch should show DNA polymerase I after it has entirely replaced the primer with DNA; label the point of the nick in this last sketch. d. Finally, show the nucleotides to either side of the nick before and after the action of DNA ligase. In other words, draw the free ends (one 5-phosphate and one 3-hydroxyl) of the top DNA strand before ligase goes to work, and draw those same two nucleotides, now stitched together, after ligase has done its job.

Explanation / Answer

a.) 100 to 200 nucleotides at a time in eukaryotes is the strech is the primer for Okazaki fragments.

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