Problem 1 (10 points). A transmembrane protein has the following properties: 1.

Question

Problem 1 (10 points). A transmembrane protein has the following properties: 1. It has two binding sites one for solute A and one for solute B 2. The protein can undergo a conformational change to switch between two states: either both binding sites are exposed on one side of the membrane or both binding sites are exposed on the other side of the membrane 3.The protein can switch between conformations only if both binding sites are occupied or both binding sites are empty. A.) What kind of transporter is this protein? B.) Do you need to specify any additional properties to turn this protein into a symporter capable of coupling the movement of solute A down its concentration gradient to the movement of solute B up its concentration gradient?

Explanation / Answer

This protein is called Transport protein which is an integral part of transmemberane protein which helps in the transportation of material or substance in and out of the membrane.

When there is movement in bi-direction i.e., one substance moves inside the membrane along electrochemical gradient and the other moves against its electrochemical gradient fueled by ATP, then this is called secondary active transport and the protein is called Antiporter or Counter-transporter.

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