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is caused by a single gene that is located on the X chromosome. Because human fe

ID: 192012 • Letter: I

Question

is caused by a single gene that is located on the X chromosome. Because human females have two X c (XX), they have The disease two copies of this gene. Since hemophilia is recessive (h), a female must have two copies of the recessive allele to have the disease A human male (XY) on the other hand, has only one X chromosome, and so needs only one copy of the recessive allele to have the disease Complete the Punnett square below of a cross between a carrier mother (a female who carries one copy of the recessive allele and so appears normal herself) and a non-hemophiliac father 1. Drag the pink labels to the pink targets to indicate the sex dictated by the genotype in each box. (Pink labels may be used more than 2. Drag the blue labels to the blue targets to indicate whether the genotype in each box confers hemophilia, normal, or carrier status. (Blue once.) labels may be used more than once.) x"x"(carrier) mother x x"Y(normal) father Sperm from father xHy Eggsfrom- mother

Explanation / Answer

Genotype of carrier mother - XHXh.

Genotype of normal father - XHY.

Cross between carrier mother and normal father.

Parent generation XHXh X XHY

Gametes formed XH and Xh XH and Y.

Next generation

Mother/ Father gametes XH Y XH XHXH(Normal female) XHY(Normal male) Xh XHXh(Carrier female) XhY(Hemophiliac male)