pls you guys don\'t have to write 375 words, I just need help to answer those qu
ID: 192192 • Letter: P
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pls you guys don't have to write 375 words, I just need help to answer those question in details. Thanks for your help
toyin kolawole Intense Q... Subtle Ref... Intense Re... Book Title Subtitle Subtle Em... Emphasis Intense E... Strong Quote Styles Personal Information Name: Mr. Peter Smith Age: 45 years old Gender: Male Description Mr. Peter Smith came to the medical office complaining of fatigue, asthenia, headaches, and generalized abdominal pain. Our patient tells us that he has had a high fever, but he did not take his temperature. The patient has had previous episodes of abdominal pain and arthralgia. Also, he was diagnosed with sickle cell anemia when he was a child. His father suffers from sickle cell anemia, diabetes mellitus, and essential hypertension. Our patient's mother had a right radical mastectomy due to breast cancer a few years ago, and she suffers from sickle cell anemia, like Mr. Smith and his father. There is no other remarkable pathologic family history Mr. Smith drinks alcohol at least once per month and smoke cigarettes. He has no history of drug addiction. He is allergic to penicillin and iodine. On physical examination we found: Remarkable Signs on Physical Exam by Regions Abdomen: Distended and painful on palpation, mostly on the left upper quadrant. Splenomegaly. SOMA: Joint pain · Remarkable Signs on Physical Exam by Systems Integumentary system: Yellowish skin and pale nail beds. Superficial crater-like skin lesion on the right medial ankle area. An erythematous area accompanied by edema, purulent secretion, and heat surrounds the lesion. . Respiratory system: Tachypnea Cardiovascular system: Tachycardia Lab Tests Complete blood count (CBC) .Hemoglobin electrophoresis . Abdominal ultrasound EKGExplanation / Answer
Answer 3:- Process where sickle cell anaemia induced ischaemia are as
Deoxygenation leads to polymerization of haemoglobin which inturn lead to sickling of red cell where there shape get change and then it cause endothelial damage than vasoconstrictions takes place where RBC and leukocyte get adhere to endothelium and then it results in vascular occulasion, organ inschemia which tend to takes place a organ damage.
Difference between ischemia and necrosis is Ischaemia leads to lack of supply of oxygen, where tissue can survive without optimum oxygen supply of anaerobic respiration and tissue don't die without oxygen where necrosis occur if ischemia lived for too long process leads to necrosis which means tissue death.
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