(2 pts) Which of the following is NOT a feature of the \"induced-fit\" model of
ID: 192308 • Letter: #
Question
(2 pts) Which of the following is NOT a feature of the "induced-fit" model of protein-ligand interaction? 13. a. Shapes of ligand and binding site are generally complementary but not an exact match. b. Conformational changes can occur in the binding site upon initial contact with its ligand. c. Conformational changes can occur in a ligand as well as in a binding site. d. Conformational changes increase the number of noncovalent ligand-binding site contacts e. A given binding site can interact with only one ligand. 14. (6 pts) On the original Star Trek, Mr. Spock once 100 explained to Captain Kirk and Dr. McCoy that Vulcan hemoglobin (and presumably myoglobin) contains copper rather than iron, which is why his skin was sort of green I guess. Anyway, I searched through Star Fleet medical records and found the Oz-binding curves for Vulcan hemoglobin and myoglobin shown on the right. a. Is O2 binding to Vulcan hemoglobin cooperative as s0 it is in human hemoglobin (yes or no)? You can tell that this is true because the shape of the O-binding curve for Vulcan hemoglobin is hvperbolic /linear /sigmoidal. (Circle the correct choice.) b. The O-binding curve for myoglobin looks different from the curve for hemoglobin because myoglobin contains oxygen binding site(s) while hemoglobin containsEnter the correct numbers, assuming that the structures of Vulcan myoglobin and hemoglobin are the same as in humans except for the copper vs. iron thing.Explanation / Answer
1. C is wrong. As, no change of conformation in ligand occurs.
2. No because the shape of the sigmoid differs.
Sigmoidal
Myoglobin 1, hemoglobin 4
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.