Select the FALSE statement regarding nucleosome structure. Question 1 options: T

ID: 193544 • Letter: S

Question

Select the FALSE statement regarding nucleosome structure.

Question 1 options:

The tails of histone H3, H4, H2A, and H2B protrude from the nucleosome core through the DNA

The nucleosome core has two of each histone: H2A, H2B, H3, and H4

Histones form hydrogen bonds with DNA bases in the major groove of the double helix

Histones prefer to assemble on bent AT-rich DNA

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Question 2 (1 point)

Packaging of DNA involves all of the following except:

Question 2 options:

supercoiling of the DNA molecule.

wrapping DNA around basic proteins.

the use of topoisomerases.

wrapping DNA around acidic proteins.

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The tails of histone H3, H4, H2A, and H2B protrude from the nucleosome core through the DNA

The nucleosome core has two of each histone: H2A, H2B, H3, and H4

Histones form hydrogen bonds with DNA bases in the major groove of the double helix

Histones prefer to assemble on bent AT-rich DNA

Que 1

Ans:

The FALSE statement regarding nucleosome structure is: Histones forms hydrogen bonds with DNA bases in the major groove of the double helix.

Explanation:

- Hydrogen bonds are formed between histone proteins, and the DNA backbone and minor groove.

Que 2.

Ans:

Packaging of DNA involves all of the following except: wrapping DNA around acidic proteins.

Explanation:

- Packaging of DNA involves supercoiling of the DNA molecule, wrapping DNA around basic proteins and the use of topoisomerases.

- Packaging of DNA involves supercoiling of DNA by topoisomerases and histone like proteins that bind to DNA and make it more compact.

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