Question 13 (1 point) Which of the following statements is FALSE concerning type

ID: 193580 • Letter: Q

Question

Question 13 (1 point)

Which of the following statements is FALSE concerning type II topoisomerases?

Question 13 options:

Drugs based on Topo II inhibitors are potent antibiotics

Drugs based on Topo II inhibitors trap the covalent enzyme DNA complex

Topo II's use an active site serine to bind directly to DNA

In the presence of Topo II inhibitors cells accumulate double stranded DNA breaks

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Drugs based on Topo II inhibitors are potent antibiotics

Drugs based on Topo II inhibitors trap the covalent enzyme DNA complex

Topo II's use an active site serine to bind directly to DNA

In the presence of Topo II inhibitors cells accumulate double stranded DNA breaks

Type II topoisomerases are the enzymes which cut DNA strands to control topology of DNA.

These enzymes usually form covalent bond with the active site of tyrosine amino acid and

bind directly to DNA.

Hence the statement c is the answer.

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