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G protein-coupled receptors (GPCRs) transform external stimuli to intracellular

ID: 19408 • Letter: G

Question

G protein-coupled receptors (GPCRs) transform external stimuli to intracellular signals. The G protein associated with the repeator is activated by legend binding,regulating an ozomine that procedure a messenger. The second messenger, in turn. Brings about changes within the cell. Components of two common second messenger pathways are given below. Identify the next component of each signaling pathway. Each compound or Ion may be used once or more than once. One target requires two answers. The following abbreviations are used: cAMP, cyclic AMP; DAG, diacylglycerol; IP3,inositol triphosphate; PIP2, phosphatidylnositol 4,5-bisphosphate: PKA, protein kinase A (cAMP-dependent protein kinase); PKC protein kinase C: PLC, phospholipase C.

Explanation / Answer

IP3 --> Ca2+ PIP2 and PLC --> DAG cAMP --> PKA Ca2+ --> PKC ATP and adenylyl cyclase --> cAMP DAG --> IP3