INCORRECT. This statement is true. Both enzymes use NAD+ and produce NADH, so bo

Question

INCORRECT. This statement is true. Both enzymes use NAD+ and produce NADH, so both are more active when the levels of NAD+ are high. Which of the following statements about the pyruvate dehydrogenase complex and the -ketoglutarate dehydrogenase complex is FALSE? Both complexes require at least 3 different cofactors. Both complexes are inhibited by the high energy thioester acetyl-CoA O The products of the reactions catalysed by both complexes can be used as biosynthetic precursors. Both catalyze oxidative decarboxylation reactions Their rates are both increased when the NAD+/NADH ratio in the cell is O high

Explanation / Answer

Both completed are inhibited by high energy thioester acetyl coA. This statement is False. AlphaKetoglurate is upregulated by coASH, ADP +Pi, Ca2+. And inhibited by high ATP, high NADH and high SuccinylCoA concentration

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