For each population group how do you think their PC mutatios casused decresod PC

Question

For each population group how do you think their PC mutatios casused decresod PC ctivity, based what you know about the PC mechanism? (3 pts) 5. In the pentose phosphate pathway (PPP), glycolytic intermediates glyceraldehyde-3-phosphate (GAP) and fructose-6-phosphate (F6P) are produced from glucose-6-phosphate (G6P) after one full tunover to GAP and F6P? Draw the structures of all products that would contain "C, cireling the labeled 1C position(s). (4 pts) (A) If G6P is "C-labeled at the C2 position, where does this radiolabel end up in the PPP (B) Where does the 'C label end up if the PPP products you drew in Part (A) then undergo gluconeogenesis followed by a second round of the PPP? Draw the structures of all "C-containing roducts of this second full round of the PPP, circling the positions of the C label(s). (4 pts)

Explanation / Answer

7. Ans-

Glycolysis is the process of conversion of a molecule of glucose into 2 pyruvate molecules. Further, this pyruvate molecule is converted into lactate or ethanol. The first metabolic pathway, glycolysis is an ancient pathway that used by a host of organisms and was discovered in 1940 by Gustav Embden, Otto Meyerhof, Carl Neuberg, Jacob Parnas, Otto Warburg, Gerty Cori, and Carl Cori and also known as the Embden-Meyerhof pathway.

Gluconeogenesis is the process of conversion of non-carbohydrate carbon substrates such as lactate, glycerol, and glucogenic amino acids into a glucose molecule. The mechanism in which lactate is produced in muscle and used by the liver and then convert into glucose (Cori cycle) was proposed by Carl and Cori in 1929.

From the above point, it is cleared that gluconeogenesis is evolved first.

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