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part B please Imagine that you have developed a genetic test to detect the domin

ID: 198327 • Letter: P

Question

part B please

Imagine that you have developed a genetic test to detect the dominant allele (A) that cause a rare genetic condition. As with most clinical tests, it isn't perfect. When a person does have the dominant allele (Aa or especially rarely AA) your test detects it 100% of the time. But, 0.5% of people who are homozygous recessive (aa) also test positve by your test. Assume 1 out of every 100 people ina population has the dominant allele (Aa or AA). Part A - What percentage of the population will give a positive test? A) 0.495%, B) 1.495% c) 1.000%, D) 99.000%, E) 98.505%, F) 99.505% Part B - If a person tests positive, what is the probability that they actually have the dominant allele (AA or Aa)? A) 0.111, B) 0.331, C) 0.889, D) 0.005, E) 1.000, F) 0.669

Explanation / Answer

Part A) What percentage of the population will give a positive result?

B) 1.495%

Part B) What is the probability that the person actually have dominant allele (AA or Aa)?

A) 0.111

As it described, AA or Aa is responsible for causing this genetic condition (1% of total population). So, the probablity will be 0.111.