Which of the following is NOT true? Proteins bearing N-linked oligosaccharides o
ID: 198546 • Letter: W
Question
Which of the following is NOT true?
Proteins bearing N-linked oligosaccharides obtain their sugar modifications in the rough endoplasmic reticulum.
The trans Golgi network is thought to function mainly as a sorting area for cargo (proteins etc) while the cis Golgi network is thought to function mainly for targeting cargo to organelles other than the endoplasmic reticulum.
O-linked sugar modifications are added to proteins in the Golgi with specific modifications made within each of the different cisternae.
Integral membrane proteins are often synthesized in the endoplasmic reticulum.
A)Proteins bearing N-linked oligosaccharides obtain their sugar modifications in the rough endoplasmic reticulum.
B)The trans Golgi network is thought to function mainly as a sorting area for cargo (proteins etc) while the cis Golgi network is thought to function mainly for targeting cargo to organelles other than the endoplasmic reticulum.
C)O-linked sugar modifications are added to proteins in the Golgi with specific modifications made within each of the different cisternae.
D)Integral membrane proteins are often synthesized in the endoplasmic reticulum.
Explanation / Answer
A Proteins bearing N-linked oligosaccharides obtain their sugar modifications in the rough endoplasmic reticulum.
Biosynthesis of all N-linked oligosaccharides begins in the rough ER with addition of a large preformed oligosaccharide precursor. But modifications to N-Linked oligosaccharides are completed in the Golgi Complex
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