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Individuals with Klinefelter syndrome have an XXY set of sex chromosomes. Which

ID: 199140 • Letter: I

Question

Individuals with Klinefelter syndrome have an XXY set of sex chromosomes. Which of these describes a way this abnormality can arise? Select all that apply.

Nondisjunction during Meiosis I in the father results in an XY sperm, which fertilizes an X egg

Nondisjunction during Meiosis II in the mother results in an XX egg, which is fertilized by a Y sperm from the father

Nondisjunction during Meiosis I in the mother results in an XX egg, which is fertilized by a Y sperm from the father

Nondisjunction during Meiosis II in the father results in an XY sperm, which fertilizes an X egg

Explanation / Answer

All of the answer are correct

Note- nondysjunction can arise during meiosis 1 or 2 during gamete formation, which cause failure of chromosome to move apart during cell division and causing two chromosome to move together toward one pole during division.

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