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Advanced maternal age is believed to be associated with trisomies because A beyo

ID: 199471 • Letter: A

Question

Advanced maternal age is believed to be associated with trisomies because A beyond the age of 35 a woman's child-bearing years are essentially over, and multiple developmental defects in the child are inevitable B the loss of female hormone levels leads to incomplete Oogenesis C women of advanced age typically have husbands of advanced age, and it is in fact gametogenesis in the male that leads to the trisomies D the egg in human females initiates meiosis during fetal development then arrests, and e long arrest is thought to lead to errors

Explanation / Answer

Answer: (D) the egg in human females initiates meiosis during fetal development then arrests, and long arrests is thought to lead to errors.

Explanation:

Baby girls are born with a certain number of "pre-egg" cells that are arrested at an early stage of meiosis. The pre-egg cell does not complete meiosis until fertilization has occured.

The long arrest may accumulate damaging mutations and errors that may affect the remaining steps of meiosis.

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