Answer the question in bold below the figure using the data presented below 1600

Question

Answer the question in bold below the figure using the data presented below 1600- 300 1200 k f 100 2 400 OXT 0 40 AVP 0 4 (Hg/ml) Li Sun et al. PNAS 2016:113:164-169 The effects of Oxytocin (Oxt) injection on serum vasopressin (Avp) levels and Avp injections of Oxt levels. Two-month-old wild-type mice were injected twice with Oxt or Avp (4 g/mL, 12 h apart) and were killed 12 h after the second injection. Which of the following accurately summarizes the findings presented above? o There was a significant reciprocal relationship between Oxt and Avp, as mice injected with Oxt had significanty higher levels of serum Avp and mice injected with Avp had significantly higher levels of Oxt. The data show that there is reciprocal regulation of Avp and Oxt secretion in mice-Oxt injections cause decrements in Avp, and vice versa. o The data show that there is not a reciprocal regulation of Avp and Oxt secretion in mice-Oxt injections cause decrements in Avp, however, the Avp injection did not affect Oxt levels o Mice injected with Oxt had increased serum levels of Avp, whereas those injected with Avp had reduced serum levels of Oxt compared with vehicle-injected controls. o

Explanation / Answer

The correct answer to the question is option B.

In the first graph, we see that when the mouse was injected with injections of Oxt (1st graph) , the level of serum vasopressin (Avp) decreased from 1300 pg/ml to 500 pg/ml.

In the second graph, levels of serum oxytocin decreased from 250 pg/ml to 125 pg/ml on injecting the mouse with 4 ug/ml of AVP.

In both the cases, levels of AVP and OXT decreased on injecting with OXT and AVP respectively.

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