1. A female Drosophila has X chromosomes of the constitution+++/abcdef A recessi

Question

1. A female Drosophila has X chromosomes of the constitution+++/abcdef A recessive lethal mutation is located somewhere on the left chromosome, but you don't know where. The phenotypes of 1000 male progeny of this cross were: P-abcdef 750 def cdef bcdef 30 70 n c abcde a b cd a b c 60 20 30 The order of genes is as shown. For the sake of simplicity, the much less frequent double crossover progeny are not shown. Using these data, map the distances between the genes and determine the location of the recessive lethal ++ 30R 36 70

Explanation / Answer

The lethal mutation are identified to be located between C and D. Hence, abc++l+ indicates that the occurence of lethal mutation after the location of C in the chromosome constitution of double crossover progeny, while the +++de+f indicates that the occurrence of viable gene located complementarily to the position of lethal mutation of abc+++l+ in the chromosome constitution of the double crossover progeny.

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