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Translocation occurs when a piece of chromosome breaks off and is lost. (Points:

ID: 20074 • Letter: T

Question

Translocation occurs when a piece of chromosome breaks off and is lost. (Points: 1)
True
False


2. Variations of homologous genes that result in differences in structure and function are: (Points: 1)
alleles.
loci.
autosomes.
dominant.
linked.


3. If both alleles of a particular gene are identical, the person is said to be (Points: 1)
an identical twin.
phenotypic.
heterozygous.
homozygous.
genotypic.


4. Red-green color blindness is an X-linked recessive disorder. Assume that mom is a carrier and dad is color blind. What is the chance that their son will inherit red-green color blindness? (Points: 1)
0%
25%
50%
75%
100%


5. A couple has a daughter who is color-blind. The mother is not color-blind, but the father is. What is the genotype of the mother for this trait? (Points: 1)
two dominant alleles
one dominant allele, one recessive allele
three dominant alleles
one abnormal Y chromosome, one normal X chromosome
two recessive alleles


6. Which of the following genotypes results in a female phenotype? (Points: 1)
XY
XYY
X
XXY
both X and XXY


7. Which of the following is true regarding Klinefelter syndrome? (Points: 1)
sterility and shows mild mental impairment
female phenotype
XYY genotype

due to nondisjunction of chromosomes after fertilization
trisomy 18 genotype


8. Which of the following is not true regarding Tay-Sachs disease? (Points: 1)
This disease is caused by a dominant-lethal allele.
Tay-Sachs disease is fairly common among Ashkenazi Jews of Central European descent.
Carriers of this disease do not have any symptoms of the disease.
Genetic tests are available to determine if an individual is a carrier of the disorder.
Symptoms of the disease result from an enzyme deficiency.


9. During DNA replication, a _____added to DNA template serves as the beginning site of nucleotide addition. (Points: 1)
DNA polymerase
5' OH end of sugar group
3' OH end of sugar group
primer
poly A tail


10. A small amount of DNA was located at a crime scene. Which of the following techniques is most likely to be used to amplify the DNA so it can be identified more accurately? (Points: 1)
genetic engineering
use of DNA ligase to recombine the pieces of DNA
gene therapy
DNA sequencing
polymerase chain reaction


11. One of the first uses of transgenic bacteria involved their production of human: (Points: 1)
heart muscle.
hormones.
skin.
plasmids.
blood vessels.


12. Which of the following human proteins, produced by transgenic bacteria, is used to prevent or break down blood clots? (Points: 1)
insulin
tissue Plasminogen activator
erythropoietin
growth hormone
factor VIII


13. Pharmaceutical companies prefer to genetically engineer large animals with human genes because it may be possible to obtain large amounts of the resulting protein from the animals': (Points: 1)
milk.
fur.
blood.
meat.
bones.


14. Which of the following is not considered a potential problem when using retroviruses as gene delivery vectors? (Points: 1)
Retroviruses splice their own RNA-based genetic code permanently into the DNA of the cells they infect.
Retroviruses generally insert foreign DNA into a cell only when the cell is dividing.
Retroviruses insert their genetic material randomly in the genome.
Retroviruses must be rendered harmless before being used.


15. The first successful treatment of a human genetic disorder through gene therapy was with a disorder known as: (Points: 1)
severe combined immunodeficiency disease.
diabetes mellitus.
human dwarfism.
hemophilia.
acquired immune deficiency syndrome.

Explanation / Answer

Translocation occurs when a piece of chromosome breaks off and is lost. (Points: 1)

False


2. Variations of homologous genes that result in differences in structure and function are: (Points: 1)
alleles.



3. If both alleles of a particular gene are identical, the person is said to be (Points: 1)

homozygous.



4. Red-green color blindness is an X-linked recessive disorder. Assume that mom is a carrier and dad is color blind. What is the chance that their son will inherit red-green color blindness? (Points: 1)

50%



5. A couple has a daughter who is color-blind. The mother is not color-blind, but the father is. What is the genotype of the mother for this trait? (Points: 1)

one dominant allele, one recessive allele


6. Which of the following genotypes results in a female phenotype? (Points: 1)

X



7. Which of the following is true regarding Klinefelter syndrome? (Points: 1)

XYY genotype




8. Which of the following is not true regarding Tay-Sachs disease? (Points: 1)
This disease is caused by a dominant-lethal allele.


9. During DNA replication, a _____added to DNA template serves as the beginning site of nucleotide addition. (Points: 1)

primer



10. A small amount of DNA was located at a crime scene. Which of the following techniques is most likely to be used to amplify the DNA so it can be identified more accurately? (Points: 1)

polymerase chain reaction


11. One of the first uses of transgenic bacteria involved their production of human: (Points: 1)

hormones.



12. Which of the following human proteins, produced by transgenic bacteria, is used to prevent or break down blood clots? (Points: 1)

erythropoietin



13. Pharmaceutical companies prefer to genetically engineer large animals with human genes because it may be possible to obtain large amounts of the resulting protein from the animals': (Points: 1)
milk.



14. Which of the following is not considered a potential problem when using retroviruses as gene delivery vectors? (Points: 1)

Retroviruses must be rendered harmless before being used.


15. The first successful treatment of a human genetic disorder through gene therapy was with a disorder known as: (Points: 1)
severe combined immunodeficiency disease.

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