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er 6, Question 4 14of17 gure below lustrates enzyme activities as functions of e

ID: 201044 • Letter: E

Question

er 6, Question 4 14of17 gure below lustrates enzyme activities as functions of erature and pH. In general, the activity of a specific enzyme hest at the temperature and pH that are characteristic of nvironment in which the enzyme nomally functions Part A Explain the shapes of the curves in the figure in terms of the major chemical or physical factors that affect enzyme activity Select all that apply Optimal temperature for Optimal temperature for a typical human enzyme atypical enzyme of thermophilik heat-tolerant) bacterla Reaction velocity increases above the temperature which corresponds to the optimum of the enzyme. This is consistent with the effect of temperature on chemical reactions in general The reaction velocity increases steadily as the temperature is increased from a colder temperature to the temperature optimum of the enzyme, consistent with the effect of temperature on chemical reactors n general Each enzyme has a temperature optimum that is at or near the Semperature of the organism The pH optimum for an enzyme corresponds to the proton concentration at which ionizable groups on the enayme and 0 20 4 00 the substrate molecules the most ionzed. As the temperature is raised above the optimum of the enzyme, it undergoes thermal denaturation the substrate molecules are in the most favorable form for chemical reactivity Temperature'C pH optimum for trypsin The pH optimum for an enzyme corresponds to the proton concentration at which lonizabile groups on the enzyme and pH optimum or pepin Submit Part B 02456789 For each enzyme in the figure, suggest the adaptive advantage of having the enzyme activity profile shown in the figure Select all that apply pH FIGURE The Eflect of Temperature and plt on the Reaction Rate of Enayme-Catalyned Reactions. Every enayme has an stimum temperature and pi that usually reflect the environment Both enzymes are maximally active at or near the pli of the neutral solution

Explanation / Answer

Increasing temperature from colder to optimum will increase the reaction rate.

An pH is optimum at which ionisable group are in best confirmation to react.

All the homeostatic organisms tend to maintain the temperature optimum for their biological processes and enzymes.

Above the optimum temperature enzymes may thermally denatured to decrease the reaction rate.