True/False (2 points each) FIIB regulates tissue or cell type-specific transcrip

Question

True/False (2 points each) FIIB regulates tissue or cell type-specific transcription. ukaryotes have three different RNA polymerases that each ca in coding genes. The P site of the ribosome refers to peptidyl. The input genetic material for RT-PCR is total RNA or purified m _The helix-loop-helix DNA binding domain binds to DNA only after en bonds between base pairs and opening up the double helix. A transcription factor can function as both an activator and repres nding on the identify of its binding partner(s). One way a transcription factor can function as a repressor is by bl ation surface of a transcriptional activator. The probability of initiating transcription of a given gene depends gration of multiple inputs provided by transcription activators, repressors vators, and co-repressors. Wobble refers to the imprecise binding of a transcription factor to it A sequence. The 5 cap of mature mRNAs has no role during translation initiation · Enhancers are gene reg ecific genes art site of transcription. ulatory elements that function in the expr ated hundreds or even thousands of base pairs 8.--Protein folding does not begin until after

Explanation / Answer

TFIIB involved in the formation of RNA polymeraseII preinitiation complex. TFIIB immobilised on a membrane and bound to several different hTR beta binding proteins in nuclear extracts from rat brain,kidney,liver,GH3 cells and HeLa cells. Hence it regulates tissue or cell type specific transcprition and it is true. Eukaryotes contains polymerases that code for protein-coding genes to yield mRNAs. Infact RNA polymeraseII intiates trancription only if additional proteins are added. But only polymerase II codes for protein coding genes,but not polymerase I and III. So it is false. The P-site(for peptidyl) is the second binding site for tRNA in the ribosome. This is true. The input genetic material in a RT-PCR can either be total RNA or purified mRNA as a template for reverse transcription. But total RNA has important advantages over purified mRNA. Hence it is true. The helix-loop-helix DNA binding domain binds to DNA only after hydrogen bonds between base pairs occurs and opening up the double helix. This is true.

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