Odorant Binding Proteins (OBP) are small, soluble proteins involved in olfaction
ID: 201570 • Letter: O
Question
Odorant Binding Proteins (OBP) are small, soluble proteins involved in olfaction. The known OBP structures indicate that the protein is an alpha + beta protein.
View the structure of porcine (pig) OBP (PDB ID =1A3Y) at rcsb.org. Display in Cartoon Style and Color by Rainbow.
Notice that there are two copies of the polypeptide displayed. Each polypeptide forms a structure that includes a beta sheet.
How many strands comprise each sheet?
Is the sheet a parallel or anti-parallel sheet?
Would you consider this structure a flat sheet, a beta-sandwich, or a beta-barrel?
Explanation / Answer
It has 9 beta sheets.
All the sheets are anti-parallel to each other.
If we look closely at the structure we will find that is forming a pore which is found only in the beta-barrel structure.
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