As we\'ve discussed, glucose uptake from blood into cells occurs via mediated tr

Question

As we've discussed, glucose uptake from blood into cells occurs via mediated transport. In liver cells, imported glucose is rapidly converted to G-6-P by glucokinase. a. (3 points) The process of phosphorylating glucose after import is considered active transport- called "transport by modification" even though ATP hydrolysis is not directly involved in transport across the membrane nor are secondary concentration gradients. Using just two or three sentences, explain how transport by modification drives glucose transport. (10 points) Given ATP maximum concentration of G-6-P inside the liver cell at 37°C, pH 7.2, when the extracellular glucose concentration is 5.0 mM. The reaction of interest in this case is b. 4.7 mM, ADP O. 15 mM, and P, = 6.1 mM, calculate the theoretical ATP + glucoseaune ADP + G-6-P + H+

Explanation / Answer

Ans- a the hydrolysis of glucose is considered as active transport because to initiate the hydrolysis of glucose ATP are required. This requirement of Atp make it to consider as active transport.

Ans- as ATP is required for hydrolysis so the G-6-P concentration will be half of glucose and ATP present as the reaction needs these both for successful hydrolysis.

4.7( ATP)+ 5.0(glucose)= 4.7(ADP)+ 4.7(G-6-P) + H+

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