Question 2: Which individual(s) definitely have cystic fibrosis? Select all the

Question

Question 2:  Which individual(s) definitely have cystic fibrosis? Select all the correct answers

Masteri blem Set 5 le ure I https://session.masteringgenetics.com/myct/itemView?assignmentProblemlD-555381offset-next roblem Set 5 estion 2 ) 2016 (> Part A Cystic tibrosis lines below th is an autosomal recessive disorder. Several different individual point mutations in the CFTR gene cause cystic fibrosis. Two of e gene represent ASO (allele specific oligonucleotide) probes and the regions of the gene in which th the most common mutations (A and B) are shown on the diagram below. The ey hybride 5 people underwent ASO testing for cystic fibrosis using all four of the probes shown above. The results of this test are shown below Which individual(s) have only the wild type sequence in the regions of both mutation A and mutation B? Select all the correct answers Mutation A Mutation B CFTR Gene -Probe #3 wild type -Probe #4 mutant Probe #2 mutant Probe #1 Probe #2 Probe #3 Probe #4 5:05

Explanation / Answer

Question 1:  Which individual(s) have only the wild type sequence in the regions of both mutation A and mutation B?

Answer: Individuals 1, 2 and 5 have only the wild type sequence in the regions of both mutation A and mutation B.

Question 2:  Which individual(s) definitely have cystic fibrosis?

Answer: Individuals 1 and 4 defiately have cystic fibrosis.

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