You generated liposomes with phospholipid and cholesterol from a solution contai

Question

You generated liposomes with phospholipid and cholesterol from a solution containing NaCl, glucose, and Phenylalanine. You precipitated the liposomes and transferred them into a solution containing distilled water. What do you expect to see after an hour?

a you will find the same concentration of phenylalanine inside and outside of liposomes

b Liposomes will be inflated

c The crystal of NaCl will be formed inside liposomes

d The liposome will build (-) membrane potential

e The solution will become highly acidic

Explanation / Answer

The correct answer will be "Liposomes will be inflated"

The liposome membrane is semi-permeable in nature and the distilled water solution is hypotonic as compared to the contents inside the liposome. As such, endosmosis will take place, i.e., water will move inside the liposome causing it to be inflated and ultimately burst.

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