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14. A G. I. Bleeder is type A, Rh negative and has never received a blood transf

ID: 202004 • Letter: 1

Question

14. A G. I. Bleeder is type A, Rh negative and has never received a blood transfusion. When performing a standard major and minor crossmatch using A, Rh positive units of blood, you would expect: a. agglutination in the minor, and not the major crossmatch b. agglutination in neither the major nor the minor crossmatch c. agglutination in the major, and not the minor crossmatch d. agglutination in both major and minor crossmatch 15. If a recipient is incompatible with only one donor, one should suspect: a. an ABO grouping error b. a recipient antibody to a low incidence antigen c. the donor has a positive direct coombs test 16. La técnica util izada para remover un anticuerpo pegado a una célula roja se conoce como: a. Adsorción b. Absorción c. Elución d. Sensitización 17. Which of the following situations will result in a major incompatibility? 1. A group A patient mistyped as o, donor is o 2. Rh neg patient mistyped as positive, donor Rh positive 3. AB patient, donor is A 4. O patient, A donor a. 1, 2 and 3 b. 1 and 2 c. only 4 d. Only 3 18. The reason for not accepting hemolyzed samples for crossmatching is: a. Hemolysis destroys complement b. Agglutination is not visible with hemolysis c. Hemolysis interferes with antigen-antibody reactions d. Previous hemolysis may mask a new hemolytic reaction

Explanation / Answer

14. c) Agglutination in major and not in minor cross match (Because in major cross match-we use to take recipient’s serum and donor’s cell where as in minor cross-match- we use to take red cells from recipient and serum from donor).

15. b) A recipient antibody to a low incident antigen.

16. Language error in question

17. c) only 4 (O patient, donor A)

18. c) Agglutination is not visible with hemolysis (RBC disrupts and releases haemoglobin).

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