From the list below: Which is the best pick during the formation of a tetrameric

Question

From the list below: Which is the best pick during the formation of a tetrameric protein quaternary structure- aggregation?

A. Lysine polypeptide 1::::::Arginine polypeptide 3

B. Alanine polypeptide 2::::: Arginine polypeptide 4

C. Amino N-end of polypeptide 2::::: Aspartate polypeptide 4

D. Glutamine polypeptide 1::::Cysteine polypeptide 3

In beta-pleated sheet structures _______

A. the interaction within the backbone is independent of the nature of the amino acid side chain.

B. peptide bonds interact regardless the position in the primary sequence.

C. could be parallel or anti-parallel.

D. all above correspond to beta sheets.

Explanation / Answer

1) Lysine polypeptide 1 - Arginine polypeptide 3 - A tetrameric polypeptide contains 4 subunits of polypeptide chains. Lysine polypeptide 1 - Arginine polypeptide 3 has one lysine polypeptide and three arginie polypeptide and is a heterodimer. The interactions between polypeptides are determined by the non-covalent interactions of the subunits.

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