3. Reflection from a single red blood cell: A transducer generating a long 10 MH

Question

3. Reflection from a single red blood cell: A transducer generating a long 10 MHz pulsed wave radiation at an acoustic pressure amplitude of 1MPa, is used in experiment to measure acoustic scattering off a single red blood cell (RBC). The same transducer is used to receive the backscattered echo. The RBC is embedded in tissue mimicking gel having an attenuation similar to that of tissue. Suggest a suitable (approximate) model for the RBC scattering cross-section and calculate the back scattered echo pressure at the transducer. Assume the distance is 2.0 cm and the gel amplitude attenuation coefficient is 10 dB/cm at 10 MHz. The diameter of the active area of the transducer is 0.4 cm.

Explanation / Answer

Quantitative Ultrasound techniques using the Radio Frequency backscattering of signals have been employed for a long time to detect and characterize tissues. One model is to use the frequency dependence and the magnitude of the radio frequency backscatter spectrum to detect and quantify the structure of tissues.

Now when we talk about the RBC cross section, models of light scattering methods come handy to study the morphology of the unstained cells.

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