#3 NOTE: I post this three-time because someone duplicated answer, please don\'t

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#3

NOTE: I post this three-time because someone duplicated answer, please don't duplicate answer I need two different views. Thanks

PLEASE, PLEASE, PLEASE, FOLLOW THE INSTRUCTOR. I DONT NEED JUST SOMETHING, I NEED YOU TO ANSWER WHAT I NEED. PLEASE DONT ANSWER IF YOU CANT DO EXACTLY I NEED. ALSO, PLEASE DO NOT COPY FROM ANY WEBSITE, IT HAS TO BE YOUR OWN WORD.

1. CHOOSE ONE OF TOPIC I LISTED

2.WHY YOU CHOOSE THIS PARTICULAR TOPIC

3. INCLUDE YOUR REPUTABLE SOURCE

4. REFERENCE

week's topic is cancer. Please write a paragraph about any topic that has reference to cancer and please tell me WHY (1 pt) you chose your topic (you must include why you chose your topic to earn full credit). Duplicate topics are acceptable because you will each have your own reasons. As always, please include your reputable source (0.5 pt) to earn full credit.

Although the list is endless, here are some suggestions: PLEASE USE THE TOPIC I PROVIDED ===> LINKS BELLOW

http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted (Targeted Cancer Therapies - scroll down to the bottom of the article to see drugs that have been FDA approved to target different cancers)

http://cancer.sanger.ac.uk/cancergenome/projects/census/ (COSMIC - Catalog of somatic mutations in cancer - this lists information about 522 different cancer genes)

http://www.acgtfoundation.org/ (Alliance for Cancer Gene Therapy)

http://www.biooncology.com/pipeline-molecules  (cancer research pipeline molecules)

http://www.proton-therapy.org/howit.htm and http://www.cancer.net/navigating-cancer-care/how-cancer-treated/radiation-therapy/proton-therapy (proton therapy)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462607/ (Ipilimumab (Yervoy) Prolongs Survival in Advanced Melanoma)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128689/ (Palbociclib: an evidence-based review of its potential in the treatment of breast cancer)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291972/ (miR-3156-3p is downregulated in HPV-positive cervical cancer and performs as a tumor-suppressive miRNA)

https://www.ncbi.nlm.nih.gov/pubmed/28218725 (Treating Cancer by Targeting Telomeres and Telomerase)

https://www.ncbi.nlm.nih.gov/pubmed/28217707 (microRNA regulation of human pancreatic cancer stem cells)

https://www.ncbi.nlm.nih.gov/pubmed/28210556 (Are breast cancer stem cells the key to resolving clinical issues in breast cancer therapy?)

https://www.ncbi.nlm.nih.gov/pubmed/28209166 (Intra-tumor heterogeneity from a cancer stem cell prospective)

https://www.nih.gov/news-events/nih-research-matters/how-elephants-defend-against-cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135649/ (Li-Fraumeni Syndrome)

https://www.cancer.org/latest-news/why-lung-cancer-strikes-nonsmokers.html

https://www.ncbi.nlm.nih.gov/pubmed/27610367 (Uncovering Driver DNA Methylation Events in Nonsmoking Early Stage Lung Adenocarcinoma)

Explanation / Answer

1. Lung cancer affecting non smokers

2. This topic interests me as it provides lot of awareness to general public. Most people dont have bad habit of smoking still they get lung cancer. This article gives us a clue what can be the other factors leading to lung cancer.

Five causes of lung cancer in non smokers

1. Radon gas: Radon gas, a naturally-occurring gas that forms when uranium decays, is another known cause of lung cancer. Those who do smoke and are exposed to radon have an even greater risk of developing lung cancer than non-smokers who are exposed to radon gas. Radon gas can travel up through soil and enter homes through gaps in the foundation, pipes, drains, or other openings.

2. Asbestos: Asbestos is a compound that was widely used in the past as both thermal and acoustic insulation material. Microscopic fibers of asbestos break loose from the insulation material and are released into the air where they can be inhaled into the lungs. Asbestos fibers can persist for a lifetime in lung tissue following exposure to asbestos. Both lung cancer and a type of cancer known as mesothelioma are associated with exposure to asbestos.

3. Passive smoking: Passive smoking, or the inhalation of tobacco smoke from other smokers sharing living or working quarters, is an established risk factor for the development of lung cancer. Non-smokers who reside with a smoker have a 24% increase in risk for developing lung cancer when compared with other non-smokers.

4. Heredity, since all smokers do not eventually develop lung cancer, it is likely that other factors, such as individual genetic susceptibility, may play a role in the causation of lung cancer. Numerous studies have shown that lung cancer is more likely to occur in both smoking and non-smoking relatives of those who have had lung cancer than in the general population

5. Air pollution from vehicles, industry, and power plants, can raise the likelihood of developing lung cancer in exposed individuals. It has been estimated that up to 2,000 lung cancer deaths per year may be attributable to breathing polluted air, and many experts believe that prolonged exposure to highly polluted air can carry a risk for the development of lung cancer similar to that of passive smoking.

Reference:  https://www.cancer.org/latest-news/why-lung-cancer-strikes-nonsmokers.html

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