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In the case of androgen insensitivity syndrome, individuals with the sex 8. irue

ID: 204070 • Letter: I

Question

In the case of androgen insensitivity syndrome, individuals with the sex 8. irue or False: constitution XY appear to be female 29. True or False: Equalization of the amount of expression of X-linked genes in males and females is accomplished via random X chromosome inactivation in females in ALL species. 30. In cats, the X-linked coat color allele X. encodes black fur and the X-linked coat color allele Xo encodes orange fur. What genotypes can result in a calico or tortoiseshell coat color (mixed black and orange) in female cats? In male cats? 31. Who proposed that dosage compensation in mammals occurs via inactivation of a single X chromosome in females?

Explanation / Answer

Dear student,

The solution to above problems shouls be as follows:

28. True.

In androgen insensitivity syndrome, individuals are females though they have XY chromosomes. They are female because they are not receptive for androgens.

29.False.

In humans X linked expression is equalized by random inactivation. But in drosophila, the same is achieved by double expression of X linked genes in males.

30.

Genotype of female will be X+Xa.

Genotype of male will be: X+XaY

31. Dosage compensation mechanism in mammals was proposed by Mary Lyon.

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