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28. In humans a B is 2153 explanation for this difference is: polipoprotein-B in

ID: 204891 • Letter: 2

Question

28. In humans a B is 2153 explanation for this difference is: polipoprotein-B in liver is 4563 amino acids long while in intestinal cells the apolipoprotein- amino acids long and both proteins are produced from the mRNA of the same gene. The best a) some of the introns of the pre-mRNA are not removed by the spliceosomes in liver but are removed in the intestines. b) Some of the exons of the pre-mRNA are not removed by the spliceosomes in liver but are c) The pre-mRNA for this gene is RNA edited in the liver to change a sense codon to a stop codon d) The pre-mRNA for this gene is RNA edited in the intestine to change a sense codon to a stop e) The ribosomes in the liver stop translating the mRNA for this gene prematurely in the liver removed in the intestines in the middle of the RNA while this does not occur in the intestines. codon in the middle of the RNA while this does not occur in the liver but not in the intestines.

Explanation / Answer

d) The pre mRNA for this gene is RNA edited in the intestine to change a sense codon to a stop codon in the middle of RNA wile this does not occur in liver.

RNA editing is a process through which some cells can make discrete changes to specific nucleotide sequences within a RNA molecule after it has been generated by RNA polymerase.

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