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31. Which of the following choices would you predict would result if a mutation

ID: 204910 • Letter: 3

Question

31. Which of the following choices would you predict would result if a mutation occurred in a eukary ated from: OLUFSE gene in which the dinucleotide sequences at the ends of intron 1 were mut Exon 1- GT-intron 14 AG -exon2 to Exon 1- AA-intron 1-CC- exon2 a) The gene would never be transcribed. b) The gene would be transcribed but never translated. c) The gene would be transcribed but the pre-mRNA intron 1 would not be excised by the spliceosomes resulting in a longer than normal protein. d) The gene would be transcribed but the pre-mRNA exon 1 would not be excised by the spliceosomes resulting in a longer than normal protein The gene would be transcribed but the pre-mRNA exon 1 and intron 1 would both be excised

Explanation / Answer

ANS) If mutation occurred in a eukaryotic gene in which dinucleotide sequence at the ends of intron 1 were mutated from:

e) The gene would be transcribed but the pre-mRNA exon 1 and intron 1 would both be excised by the splicesomes resulting in a shorter than normal protein.

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