1. Imagine that you treat a cell with a chemical that completely inhibits the ac
ID: 205043 • Letter: 1
Question
1. Imagine that you treat a cell with a chemical that completely inhibits the activity of an enzyme that is critical for glycolysis, such that glycolysis is inactive in the cell. You then supply the cell with pyruvate. How many molecules of ATP will be made by the cell for every molecule of pyruvate you provide? (You may assume that pyruvate gets into the cell)
2. Suppose you gave the cell Acetyl-CoA instead of pyruvate. How many ATP would be made per Acetyl-CoA molecule? (You may assume that the Acetyl-CoA gets into the mitochondria)
Explanation / Answer
Answer:
1) 15 ATP
Explanation:
Pyruvate ----acetyl-CoA = 1 NADH = 3ATP
Acetyl-CoA in citric acid cycle = 3 NADH + 1 FADH2 + 1 ATP
3 NADH = 3 * 3 ATP = 9 ATP
1 FADH2 = 2 ATP
Total ATPs = 3 + 9 + 2 + 1= 15
2). 12
Explanation:
Acetyl-CoA in citric acid cycle = 3 NADH + 1 FADH2 + 1 ATP
3 NADH = 3 * 3 ATP = 9 ATP
1 FADH2 = 2 ATP
Total ATPs = 9 + 2 + 1= 12
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