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10. Angiogenesis is critical to tissue engineering success. a) Explain this stat

ID: 205385 • Letter: 1

Question

10. Angiogenesis is critical to tissue engineering success. a) Explain this statement b) How is the need for a blood supply typically substituted for during the construction and conditioning of engineered tissues in vitro? What are the limitations? c) List four different strategies you might employ to enhance vascularisation during tissue implantation IV. 11. Define a. Tissue Engineering b. Biocompatibility in relation to tissue Engineering c. Describe the elements required to develop a tissue by Tissue engineering methods 12. Mention 3 types of scaffolds that can be used in TE give examples 13. Describe 3 methods of scaffolds preparation, give examples a method to promote or increase cell adhesion on scaffolds a. b. 14. What is understood by extracellular matrix (ECM)? 15. Desribe 3 components of the ECM different to collagen 16. Is it possible to use ECM as a scaffold? Explain why? 17. Give 3 types of cells thah can be used in TE. What is her mechanism and how function? 18. Establish the difference between embryonic stem cells and adult stme cells 19. Is possible to use differentiate cells in TE? Why? 20. Describe how mechanical forces can influence the quality of a tissue obtained by TE Provide References for your Answers

Explanation / Answer

as per chegg guidelines if you post more than 1 question i have to answer only one.

ques14) EXTRACELLULAR MATRIX -- are extracellular molecules which are collected together that then provides structural and biochemical support to the surrounding cells. interstitial matrix and the basement membrane combinely called extracellular matrix. proteoglycans, water, minerals, and fibrous proteins together make ECM.

FUNCTION OF ECM--

egs-- ground substance is the ECM of connective tissue

blood plasma is ECM of blood

collagen and bone mineral is ECM of bone tissue etc.

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