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be differences in the \"sides\" of a cell when we talk about cellular polarity.

ID: 205900 • Letter: B

Question



be differences in the "sides" of a cell when we talk about cellular polarity. (3pts) The membranes of cells also show "polarity". Name at least 3 separate characteristics of the membrane in the image below that illustrate polarity 1. Chol 0 Gang SPM OPI TM1 TM2 Acyl cytoplasm 2. (3pts) The blue shaded regions of the membrane are lipid rafts, which show differences in lipid and protein composition from other parts of the membrane. These differences restrict movement of molecules into and out of the raft and also molecules within the raft. Which of the following would you expect within a lipid raft? choose three answers a. increase in cholesterol content b. decrease in cholesterol content c. increase in glycosphingolipids with longer fatty acid tails d. increase in glycosphingolipids with shorter fatty acid tails e. increase in unsaturated phospholipids f increase in saturated phospholipids

Explanation / Answer

Ans

1. characterstics of the membrane that illustrate polarity -

a) glycolipids and GPI - linked proteins are exclusively located on the outer leaflet of the plasma membrane. the carbohydrate groups are exposed to the outer surface.

b) The outer leaflet of the plasma membrane consists mainly of phosphatidylcholine and sphingomyelin (assymetrical distribution)

c) phosphatidylethanolamine and phosphatidylserine are the predominant phospholipids of the inner leaflet. A fifth phospholipid, phosphatidylinositol, is also localized to the inner half of the plasma membrane.

2. following are expected within a lipid raft.

a. increase in cholesterol content .

b. increase in glycosphingolipids with longer fatty acid tails.

c. increase in saturated phospholipids.

This composition results in lateral phase separation and the generation of a liquid-ordered domain..