(2+2+2 points) In class we discussed the use of monoclonal antibodies to treat d
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Question
(2+2+2 points) In class we discussed the use of monoclonal antibodies to treat disease. a) b) 9. State two benefits of monoclonal antibodies compared to synthetic pharmaceuticals. What are the differences between a chimeric, humanized, and human monoclonal antibody therapeutic? c) Although there are certain applications that require antibody fragments (Fab) that lack an Fe region, in general, the Fc region promotes antibody therapeutic function. Describe how the Fo region plays an important role in antibody function.Explanation / Answer
Monoclonal antibodies produce antibody
Side effects can be treated by different ways.
They are giving speedy result because they are specific.
Chimeric antibodies:- Antibodies produced by fusion of antigen binding region of variable domain (Heavy and light chain) and constant region from another species.
Humanized antibody:- These antibodies are produced by combining antibody from human and monoclonal antibody from another species like mouse, rat.
human monoclonal antibody:- B cells are used for production of this antibody.
Fc region promotes phagocytosis which is helpful in destroying antigen.
Antibody dependant cell mediated cytotoxicity is important mechanism for destroy antigen.
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