0 NAD mtochonaal #3 in the figure above is cytochrome c. cytochrome c oxidase is

Question

0 NAD mtochonaal #3 in the figure above is cytochrome c. cytochrome c oxidase is shown below #4 is cytochrome c oxidase. The reaction catalyzed by 4 Fe2+-cytochrome c + 8 H.in + 02 4 Fe».cytochrome c + 2 H2O + 4 H.out The poison cyanide binds irreversibly to cytochrome c oxidase preventing it from carrying out the reaction above 1. Consequently, cyanide has a direct effect on a specific function of the pathway. What specific effect is this? Consider the equation above Consider your answer to question 1. In one sentence, what indirect effect does cyanide have on oxidative phosphorylation? 2.

Explanation / Answer

1. The direct effect will be inhibition of the cytochrome c oxidase as a result of which there would inhibition of the cellular oxygen.

2. Indirect effect will be inhibition of the production of ATP followed by inhibition of the oxidative phosphorylation in the mitochondria.

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