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uppose that 200,000 Mexican-American men were screened with Prostate-Specific An

ID: 208049 • Letter: U

Question

uppose that 200,000 Mexican-American men were screened with Prostate-Specific Antigen (PSA) for prostate cancer for the first time at M.D. Anderson Cancer Center. Of these, 8000 men had a positive result on the screening blood test (PSA 4.0 ng/mL); of those who tested positive, 1,200 had a biopsy confirming diagnosis of prostate cancer. Among the remaining men who screened negative, 100 developed prostate cancer within the following year and were assumed to be false negatives on the screen. What is the prevalence of prostate cancer in this population? (Please round to the second decimal place) Hint: Your answer should be in percentage form; therefore you must include the % sign in order to gain credit.

Prostate Cancer No Prostate Cancer TOTAL PSA (+) 1200 6800 8,000 PSA (-) 100 191,900 192,000 TOTAL 1300 198,700 200,000

Explanation / Answer

Answer = (Number of people with prostate cancer x 100 )/Total number of people screened
= (1300 x 100)/200,000
= 0.65%