Would it be E because it is looking for changes in gene expression of rRNA? If i

Question

Would it be E because it is looking for changes in gene expression of rRNA? If it isn't what would it be and why??

Down syndrome (DS) results from complete or partial triplication of human chromosome 21. It is assumed that the neurological and other symptoms are caused by changes in the expression of genes on chromosome 21 or genes on other chromosomes, but this hypothesis has not yet been assessed on a chromosome-wide basis. 6 Which one of the following techniques would best show changes in gene expression of rRNA genes in individuals with Down syndrome compared to individuals with a diploid number of chromosome 21? A. Southern Blot B. Western Blot C. Mass Spectrometry D. Density Gradient Centrifugation E Northern Blot

Explanation / Answer

E) A northern blot is a laboratory method used to detect specific RNA molecules among a mixture of RNA. Northern blotting can be used to analyze a sample of RNA from a particular tissue or cell type in order to measure the RNA expression of particular genes.

Thismethod was named for its similarity to the technique known as a Southern blot.

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