34. When it comes to enzymes finding their substrates in the cell, which of the
ID: 210084 • Letter: 3
Question
34. When it comes to enzymes finding their substrates in the cell, which of the following processes will increase the likelihood of this event and why? A. Cooling the reaction; allows for the substrate to bind to the enzyme B. Heating the reaction; increases the thermal motion of the substrate C. Heating the reaction; strengthens the interaction between the substrate and the enzyme D. Cooling the reaction; stabilizes the bond between the enzyme and the substrate 35. Which of the following bonds in unlikely to be utilized by an enzyme:substrate complex A. Covalent B. Van Der Waals forces C. Hydrogen bonds D. Electrostatic interactions 36. Consider the following reaction catalyzed by the enzyme "Halokinase A+JAJ Which of the following influences the reaction in the forward direction? A. Decreasing the concentration of A B. Decreasing the concentration of J C. Increasing the concentration of AJ D. Decreasing the concentration of AJ 37. An investigator is designing a new drug to inhibit an important enzyme in a cancer cell. To have the best properties, his drug should: A. Increase the Vmax of the enzyme B. Have a high Km for the enzyme C. Increase the 1/2Vmax of the enzyme D. Increase the concentration of the available substrate 38. A competitive inhibitor will; A. Increase the Km of the enzyme B. Decrease the Km of the enzyme C. Not affect the Km of the enzyme D. Increase the Vmax 39. Which one of the following macromolecules is not typically broken down for fuel? A. Polysaccharides B. Nucleotides C. Amino Acids D. Lipids E. Acetyl CoAExplanation / Answer
34)B) heating the reaction.
Due to heating thermal motion of both substrate and enzyme increases which lead to the increase in collision between enzyme and substrate. This lead to more molecules reaching the activation energy. Hence increases the rate of reactions.
35) C)Hydrogen bond
Bond formed between enzyme and substrate is mainly hydrogen bond or hydrophobic interaction.
36) D, decreasing the concentration of AJ.
Decrease concentration of products favour reaction in forward direction.
37) B) have a high Km for the enzyme.
Drug bind to enzyme active sites and compete to substrate for its binding. This raises Km but Vmax remain same.
38) A) increases Km.
In competitive inhibition vmax remain same.
39)B) Nucleotides
In cell polysaccharides or lipid or amino acid, are break down into simple sugar or monosachharide or in some intermediates which act as fuel for cells.
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