Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

2. As a joke, Prof. Canaan made Alice a batch of brownies cntter eating an inhib

ID: 210365 • Letter: 2

Question

2. As a joke, Prof. Canaan made Alice a batch of brownies cntter eating an inhibitor ofnsan made Alice a batch liver. W inds that only scated with metabolism. After eating these delectable of brownies containing glucose as a sweetener moles of ATP are being produced per mole of glucose in might be useful to list each enzyme enzyme a his liver. Where does the inhibitor act? Be sure to name the inhibited enzyme and the while tabulating running ATP yields. pathway with which it is usually associated. For this. it Inhibited enzyme: Pathway: Pathway Reaction or Cycle Net Gain (per glucose) e carrier ATP Produced AGIP (liver tissue) Enzyme Glycolysis PDH TCA TOTAL

Explanation / Answer

Pathway

Enzyme

Electron carrier

A/GTP, NADH

ATP Produced

Glycolysis

Hexokinase

ATP

ADP

-1

Phosphofructokinase

ATP

ADP

-1

GAPDH

NAD+

2NADH

5

Phosphoglycerate kinase

ADP

2ATP

2

Pyruvate kinase

ADP

2ATP

2

PDH

PDH

NAD

2NADH

5

TCA

Isocitrate dehydrogenase

NAD

2NADH

5

-ketoglutarate dehydrogenase

NAD

2NADH

5

Succinyl-CoA synthetase

GDP

2GTP

2

Succinate dehydrogenase

Inhibited enzyme in TCA

Total ATP produced

24

Pathway

Enzyme

Electron carrier

A/GTP, NADH

ATP Produced

Glycolysis

Hexokinase

ATP

ADP

-1

Phosphofructokinase

ATP

ADP

-1

GAPDH

NAD+

2NADH

5

Phosphoglycerate kinase

ADP

2ATP

2

Pyruvate kinase

ADP

2ATP

2

PDH

PDH

NAD

2NADH

5

TCA

Isocitrate dehydrogenase

NAD

2NADH

5

-ketoglutarate dehydrogenase

NAD

2NADH

5

Succinyl-CoA synthetase

GDP

2GTP

2

Succinate dehydrogenase

Inhibited enzyme in TCA

Total ATP produced

24