For each of the following situation, indicate the first process that would be di

Question

For each of the following situation, indicate the first process that would be directly affected in a eukaryotic cell. Acetylation of histones. Translation None of these Transcription Expression of miRNAs. Transcription pre-mRNA processing pre-mRNA processing Translation None of these Addition of a drug that blocks the function of Rat1 Transcription pre-mRNA processing Translation None of these A loss-of-function of RNA Polymerases I & IlI, but not RNA Polymerase I Transcription Translation None of these Addition of a drug that prevents RNA from leaving the nucleus. Transcription pre-mRNA processing Translation None of these

Explanation / Answer

Acetylation of Histones- Histone acetylation leads to removal of histone protein form DNA. As a result of it, the DNA is now available for transcription.

So correct answer is option A- transcription.

Expression of miRNA -

miRNA binds to the mature RNA and degrade the mRNA. If the mRNA Is degraded then there will not be the translation.

SO answer is option C. translation.

addition of drug which blocks Rat1-

Rat 1 - is the protein which helps transcriptional termination. It helps in the recruitment of other proteins which terminate transcription.

So the answer is option A- transcription.

A loss of function of RNA polymerase I and III.

RNA polymerase I synthesize ribosomal RNA

RNA polymerase III synthesizes tRNA some subunit of ribosomal rRNA.

Both tRNA and ribosomal RNA helps in translation. So the loss of function of RNA polymerase I and III. will affect translation.

So the answer is option c- translation.

A drug which prevents RNA from leaving the nucleus-

mRNA is matured inside the nucleus only. In the nucleus, all the essential enzymes which are required for mRNA synthesis form pre-mRNA are present.

matured mRNA is transported from the nucleus.

So correct answer is option C- translation  

  

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