Which of the following conversions take place in a metabolic situation that requ

Question

Which of the following conversions take place in a metabolic situation that requires more NADPH than ribose-5-phosphate, as well as the complete oxidation of glucose-6-phosphate to CO2? (The arrows represent one or more steps.)

A) glucose-6-phosphate --> ribulose-5-phosphate

B) fructose-6-phosphate --> glyceraldehyde-3-phosphate --> ribose-5-phosphate

C) ribose-5-phosphate --> fructose-6-phosphate --> glyceraldehyde-3-phosphate

D) glyceraldehyde-3-phosphate --> pyruvate

E) fructose-6-phosphate --> glucose-6-phosphate

Explanation / Answer

The correct option is C) ribose-5-phosphate --> fructose-6-phosphate --> glyceraldehyde-3-phosphate.

Much more NADPH than ribose 5-phosphate is required. The fact is that the adipose tissue requires a high level of NADPH for the synthesis of fatty acids. In this case, glucose 6-phosphate gets completely oxidized to CO2. Three groups of reactions are active in this situation.

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