Choose a type of pathogen (e.g., a virus or bacterium) and take your pathogen on

Question

Choose a type of pathogen (e.g., a virus or bacterium) and take your pathogen on a tour of the human body. Your goal is to provide the pathogen with as much information as possible so that it can effectively navigate the human immune system and establish an infection.

Write a 1,050- to 1,400-word report that answers the following questions:

1.) Choose a point of entry into the human body, and outline potential barriers the pathogen might encounter.

2.) Provide an overview of the normal flora in the human body that your pathogen may interact with, and include some challenges that the flora might present.

3.) Provide an overview of the workings of the innate immune system, including the major components. Are there ways in which your pathogen might slow down or avoid the innate immune system?

4.) Provide an overview of the workings of the adaptive immune system, including the major components. Are there ways in which your pathogen might slow down or avoid the adaptive immune system?

APA format

Explanation / Answer

Viruses are small segmentys of nucleic acid with a protein or lipoprotein coat that acquires host replication machinery for its own replication. Virus enters a cell via a cell surface receptor which activates specific immune effector meachanisms along with non specific defense mechanisms to prevent or elimate viral infections.

Innate immune response -

This response begins with the recognition of pathoge associated molecular patterns (PAMPs) and leads to the generation of antiviral effectors. dsRNA molecules and other virus specific structures are detected by PAMP receptors, inducing the expression of type I interferons (IFN alpha and beta), the activation of NK cells. Type I interferons induces an antiviral response or resistance to viral replication by binding to IFN alpha/beta receptor thereby activating JAK-STAT pathway. and leads to RNA degradation. It also leads to inactivation of viarl protein synthesis by inducing dsRNA dependent protein kinase (PKR) The binding of type I IFN to NK cell induces lytic activity and production of IL 12 produced by dendritic cells.

Related Questions

Navigate

• Browse (All)
• Browse C
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.