41) Three classmates from microbiology class are talking about drug resistance.

Question

41) Three classmates from microbiology class are talking about drug resistance. They each 41) disagree about the definition of the term so they state his or her definition and give a justification. Compare the various definitions and justifications below and pick the one that is most accurate. A) The bacterium has changed physically or chemically in some way to be able to destroy the drug or avoid its action, allowing it to grow unimpeded by the drug. no longer works properly against the bacterium. the bacterium. chemical and no longer responds to its action. B) The drug is changed in the body and is inactivated physically and chemically so it C) The bacterium becomes immune to the drug; the drug no longer kills or inhibits D) The person becomes resistant to the drug; the body adjusts to the dosage of the

Explanation / Answer

Option A is the most accurate among the given definitions.
A. The bacterium has changed physically or chemically in some way to be able to destroy the drug or avoid its action, allowing it to grow unimpeded by the drug.

Drug resistance is the ability of the microorganism to withstand the drug which was previously capable of killing the organism. The microbes evolve to become resistant to the drugs through one of the following mechanisms,
1. By degrading the drug by producing enzymes.
2. Altering the premeability of the cell membrane so that the drugs cannot enter the microbial cell.
3. By making changes in the target proteins in such a way that the drugs cannot bind to its target.

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