Use the codon table to determine which mRNA triplets code for the amino acid cys
ID: 212301 • Letter: U
Question
Use the codon table to determine which mRNA triplets code for the amino acid cysteine, Cys. Second mRNA base UAU UGU Cys UCU UUA UCA () UAA Stop UGA Stop UUGL) UCG UAG Stop UGG Trp His CGU- CCC Pro CAC (H) cGC CUA(L) (L CCA P) CAA Gln C CGA (R) CCG (Q) CGG AUU AUC AUA ACU AGU Ser AAU Asn AAC N) AGC (S) Ile ACA (T) AAA ys (K) AGA AGG(R) LGUU GAU GGU (D) GGC Gly GUC Val GCC GUA GUG (A) GAA Glu G GGA (G) GCG GAG E) GGG Select all that apply AGU UGU UGG UGC Submit Request Answer - PartB Think about the DNA coding sequence of a gene. If an A were swapped for a T, what kind of mutation could it cause and why? It could cause a silent, missense, or nonsense mutation because those are the types that can be caused by a nucleotide-pair substitution like this one It could cause a frameshift nonsense or frameshift missense mutation because it would change the reading frame of the codon triplet. It could cause a silent mutation because A and T are complementary to each other so it is not really a substitution mutation. It could cause a nonsense mutation because the sequence would no longer be the same, so the protein would be shorter and non-functional Submit Request AnswerExplanation / Answer
Ans: UGU, UGC
Codon refers to the triplet code of the gene. Each triplet specifies a single amino acid.
As per the codon table, the mRNA triplets UGU and UGC code for the amino acid Cysteine, Cys.
AGU codes for Serine
ACA codes for Threonine
UGG codes for Tryptophan
Ans: It could cause a silent, missense or nonsense mutation because those are the types that can be caused by a nucleotide-pair substitution like this one.
If Adenine (A) is swapped for a Thymine (T) it results in transversion which is the replacement of purine for a pyrimidine and vice versa. This results in substitution mutation which could either be Silent, missense or a nonsense mutation as it changes the codon and hence may alter the protein produced.
In silent mutation, even though the codon is altered, it still produces the same amino acid.
In missense mutation, the change in the single nucleotide leads to the production of a completely different amino acid hence the structure of the protein will be altered.
In nonsense mutation, the change in the single nucleotide will lead to a premature stop codon. The translation will be stopped midway and a defective/nonfunctional protein will be formed.
Since there is no insertion or deletion of a nucleotide, the reading frame remains the same and hence this substitution mutation cannot cause frame shift mutation.
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