NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE East Meets West An Infectious

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NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE East Meets West An Infectious Disease Case by Harry M. Zollars, Catherine D. Santanello, and Marcelo J. Nieto Department of Pharmaceutical Sciences Southern Illinois University Edwardsville PartI-Illness Tuesday afternoon, January 8, 201 maybe you should go to Med-Way Drugs to se if they have something besides isatis rot that will help Yings fever. Ying was sitting in the family room crying louder by the minute. He had been this way for a few days. am starting to worry because he seems hotter than he was a couple of days ago and hes complaining about not heing able to swallow because of the pain," Min exclaimed "I don't want to talk to the pharmacist about any of those Ne World drugs if that is what you are suggesting, Min i just called my Mom and she said that her herbalist in Beijing always recommends yarrow for a fever. Maybe we can try that instead." Wai suggested. His teacher told me that lots of other kids in his kindergarten class have been home sick. She said that they ate usually out for a week, so I think we need to think about a more aggressive treatment." Min added. Aggressive? These are the strongest herbs that I can find! Let's give him some hot mint tea as well. That always helped my sore throats when I was a kid." said Wai, as he started for the door. "In the meantime. I'm going to our herbalist for something more specific for his fever Wednesday morning. January 9, 2013 Ying's fever had spiked even higher despite the use of a variety of Chinese traditional treatments. His throat was erythematous and he was refusing to eat. His parents continued to worry about his condition and monitoted his progress over the weck with continued encouragement for food and Huids as well as the herbal medications Wai was recommended by his local herbalist. Questions 1. In addition to isatis root and yarrow, what are other medicinal plants that some traditional medicine 2. Mint tea is sometimes used to relieve the pain of a sore throat. What other botanicals are used for patients with 3. List the potential pathogens you think Ying may have and the rationale for including these options practitioners claim have an effect on alleviating fever? Are there any clinical trials to prove the effectiveness of each? List and research at least two. pharyngitis? Are there any OTC medications similar to mint's action for pharyngitis? Eas Meets West" by Zollans, Santanello, &Nieto; Page t

Explanation / Answer

Q ) Part-I , Illness:-

Answer :- Besides isatis root and yarrow, other medicinal plants are white willow(salix alba), Meadow sweet, Indian pipe.these plants are effectiev against alleviating fever.

Few clinical trials were made on salix alba ,or white willow ,  willow bark extracts are standardized to salicin, other ingredients in the extracts like other salicylates, polyphenols, and flavonoids .It plays an important role in treatment.

Black cohose is also used for clinical trial, a clinical trail of 286 people with acute pharyngitis were exposed to mace spray and also to placebo spray , but it is found that Black cohose is more effective than the placebo.

Q2) Besides mint tea other botanicals used to treat pharyngitis are - Marshmellows, Linden,Echinacea etc.

Marshmellow Medication is similar to mint , in marshmellow it is rich in mucilage ,and helps in smoothing the respiratory tract.

Q3) list the potential pathogens you think ying may have and rationale for including these options'

Haemophilus influenzae and groups C and G beta-hemolytic streptococci. Occasionally, existing infection with penicillin-resistant Staphylococcus aureus occurs,

Haemophilus influenzae infection- The throat and skin are the , two of the many sites for H influenzae infections in adults.

Another organism is beta hemolytic streptococci. Group A beta-hemolytic streptococcal infections. GABHS is the most common bacterial cause of tonsillopharyngitis, this organism also shows acute otitis media; pneumonia; skin and soft-tissue infections; cardiovascular, musculoskeletal, and lymphatic infections; bacteremia; and meningitis.

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