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35. Shigella dysenteriae is one of the most highly infectious pathogens What doe

ID: 213857 • Letter: 3

Question

35. Shigella dysenteriae is one of the most highly infectious pathogens What does ths indicate about the organism? a) Infection is possible after exposure through a wide range of possible direct or indirect routes, including routes that create chances for exposure during normal everyday activities failure or death b) The symptoms of an infection by S dysenteriae are severe, possibly including organ c) Infection is likely after exposure to a very smal number of microbes d) Infection with S dysenterioe is very likely to lead to disease survives and reproduces in the intestines. These living microbes also create and release a toxin called Shiga toxin. Toxins like this are called a) Endotoxins b) Anti-toxins c) Toxoids d) Exotoxins 37. Shiga toxin attacks ribosomes in host cells, interfering with protein synthesis and killing the cell Your friend bacteria need to proposes that this toxin might make an good drug for treating bacterial infections, since synthesize many proteins in order to survive and grow, but you disagree Which reasons why the Shiga toxin would make a poor antibiotic a) The Shiga toxin is relatively unlikely to be effective against bacteria, because their translational machinery of the following are valid for human use? is evolutionarily distinct from eukaryotes' b) The Shiga toxin is harmful to humans, so it would be difficult to use it for treatment c) The Shiga toxin would probably be a useful medicine for humans, d) Aand B, but not C e) A, B, and C but it is so difficult to produce and collect compounds produced by bacteria that this is not a viable method for creating a drug 38. Strains of S dysenteriae that are resistant to multiple antibiotics are becoming more common. For this reason, bacterial dysentery unless absolutely necessary some people argue that we should not use antibiotics to treat Is this a good strategy? a) Yes, because antiblotic treatment causes host cells to become resistant to the drug b) No, because antibiotics don't change whether a microbe is drug resistant or not, so using antibiotics doesn't increase resistance c) Yes, because if antibiotics are not used then drug resistant do not have an advantage over non-resistant microbes, and are less likely to spread. No, because highly infectious diseases like bacterial dysentery have extremely severe symptoms, so it is dangerous not to use antibiotics as early as possible. d) general types of tumors:which are tumors that can grow but do not spread to which invade nearby healthy tissue and spread throughout the body new tissue, and a) benign tumors/warts b) malignant tumors/benign tumors c) benign tumors / malignant tumors d) cancers/malignant tumors Genes encoding proteins that can slow or stop cell division if the dividing cell is unhealthy are called: a) Tumor suppressor genes b) Cancer protection genes c) Oncogenes d) Carcinogenes 40. Page 7

Explanation / Answer

35. Option A is correct.

Shigella is highly successful pathogen as it can get infected through multiple ways.

36. Option D is correct.

Shigella produces an exotoxin.

37. Option D is correct.

The translation machinery is different between prokaryotes and eukaryotes. Hence Shiga toxin may not be effective in bacteria. Shiga toxin is toxic to human cells.

38. Option D is correct.

Bacterial dysentery is a very severe disease. So, it has to be treated even if the bacteria evolve resistance.

39. Option C is correct.

Benign tumors = Unregulated proliferating cell mass that does not spread.

Malignant tumors = Unregulated proliferating cell mass that spreads to other tissues.

40. Option A is correct.

TSGs are negative regulators of cell proliferation.

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