Create three biochemical/glycolysis hypotheses and how to test them: You work in
ID: 213940 • Letter: C
Question
Create three biochemical/glycolysis hypotheses and how to test them:
You work in a clinic in Neither City. A 4-year old girl is brought into the emergency room by her dad after she had fainted on the playground. At the ER, she was still very pale fatigued and confused Hypothesize Based on these data, what are your top three hypotheses to explain this situation (1.5 pts each) The Dad reports that the girl was always'the quiet one' of his daughters, but recently he has been noticing that she is increasingly lacking energy and does not like to run around with other kids in her day care group. She says she is uncomfortable doing so and it makes her feel 'weak, You are an awesome physician, skilled in thinking about biochemistry in context, and you notice signs of jaundice around her eyes. You suspect that the girl has anemia caused by a metabolic enzyme deficiency in the glycolytic pathway [insert your favorite enzyme]. The fraternal twin sister of the girl does not exhibit any of these symptoms. You want to test this hypothesis related to glycolytic enzymes. This cannot be one of your three hypotheses above. Investigate State what or clinical or lab tests you would order to confirm A) your diagnosis of anemia (1pt) and B) explain how you would go about testing your hypothesis about the glycolytic enzyme deficiency that you are suspecting as underlying cause (4.5 pts)?Explanation / Answer
Hypothesis:
1.
The girl is pale and feeling fatigue might be suffering from some deficiency in the body. The first test that should be done is the blood test in such condition. This test will allow identifying any problem in the blood.
2.
The girl is looking pale which is the sign of jaundice. This girl will be suggested to go for the LFT (a test to identify the liver health). This test will help in ensuring that the girl is having any liver disorder or not.
3.
The father of this girl will be asked for the diet of the girl and regular food habits. The content of water a girl is in taking in the whole day is also important to ask. This girl is looking like she has deficiency of minerals. A test to check the dehydration can also be performed in the given situation.
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