Question 2 In 1944, Avery, MacLeod, and McCarty extended Griffith\'s experiments

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Question 2

In 1944, Avery, MacLeod, and McCarty extended Griffith's experiments by showing that the transformation activity of the purified "transforming principle" was inactivated by __________.

protease

DNase

RNase

ultracentrifugation

all of the above

1 points

Question 3

Which of the following is a key component of a DNA nucleotide?

Nitrogenous base

Deoxyribose sugar

Phosphate group

All of the above.

None of the above.

1 points

Question 4

What is the difference between purines and pyrimidines?

Purines are found in RNA while pyrimidines are found in DNA.

Pyrimidines are found in RNA while purines are found in DNA.

Purines contain a double ring backbone, while pyrimidines contain a single ring backbone.

Pyrimidines contain a double ring backbone while purines contain a single ring backbone.

None of the above.

1 points

Question 5

In a DNA molecule, what holds together the nitrogenous bases from the two sugar-phosphate backbones?

phosphodiester bonds

ionic bonds

covalent bonds

peptide bonds

hydrogen bonds

1 points

Question 6

If a DNA molecule is 30% cytosine (C), what is the percentage of guanine (G)?

30%

60%

35%

70%

15%

1 points

Question 7

With respect to their 3' and 5' ends, the two polynucleotide chains of a double-stranded DNA molecule are:

antiparallel.

methylated.

discontinuous.

nitrogenous.

none of the above.

1 points

Question 8

Replication of DNA:

takes place in a conservative manner.

takes place in a dispersive manner.

takes place in a semiconservative manner.

usually involves one origin of replication per chromosome in eukaryotes.

takes place only in the 3' to 5' direction.

1 points

Question 9

Okazaki fragments are used to elongate:

the leading strand toward the replication fork.

the lagging strand toward the replication fork.

both strands in both directions.

the leading strand away from the replication fork.

the lagging strand away from the replication fork.

1 points

Question 10

The Holliday model describes which process?

Semiconservative replication

Homologous recombination

End replication

RNA primer synthesis

None of the above.

protease

DNase

RNase

ultracentrifugation

all of the above

Explanation / Answer

2. They ruled out protien as a contemporary favorite beacuse the activity of transforming principle could be enzymatically destroyed by dNASe not proteinase.

3. There are three main components a. A sugar group (deoxyribose) b. A phosphate group c. One of four bases( cytosine, adenine, guanine, thymine).

4. Purine contains double ring backbone while pyramidine contains single ring backbone.

5. DNA molecule consists of two strands of nucleotides twisted together to form a double helix. The sugar phosphate backbone is found on outside of this helix and bases are found branching towards the middle. Hydrogen bond joins the nitrogenous bases and holds the two strands together.

6. In DNA as cystine is 30% tha guanine percentage will be same as 30% and remaining 40 will be equal parts of adenine and thymine.

8. Replication of DNA generally occurs in semiconservative method. Each strand in the double helix acts as a template for synthesis of new complimentory strand.

9. Okazaki fragments are used to elongate lagging starnds as DNA polymerase cannot start synthesis from the 5' end of the strand so to overcome this problem a loop is formed at 5' end so as to make direction analogues to other strands.

10.'

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